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- Table of Contents
Designing a Western blot for Moesin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MSN Western Blot GuideFacts about Moesin.
Plays a role in regulating the proliferation, migration, and adhesion of human lymphoid cells and participates in immunologic synapse formation (PubMed:27405666). .
| Human | |
|---|---|
| Gene Name: | MSN |
| Uniprot: | P26038 |
| Entrez: | 4478 |

| Belongs to: |
|---|
| No superfamily |

Membrane-organizing extension spike protein; moesin
Mass (kDA):
67.82 kDA

| Human | |
|---|---|
| Location: | Xq12 |
| Sequence: | X; NC_000023.11 (65588382..65741931) |
In all tissues and cultured cells studied.
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, microvillus. Phosphorylated form is enriched in microvilli-like structures at apical membrane. Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment (By similarity). Localizes at the uropods of T lymphoblasts.






PMID: 1924289 by Lankes W.T., et al. Moesin: a member of the protein 4.1-talin-ezrin family of proteins.
PMID: 7884872 by Schneider-Schaulies J., et al. Physical association of moesin and CD46 as a receptor complex for measles virus.